Prevalence and Associated Factors of Pylori Infection in Symptomatic Patients Admitted to A Major Hospital in Saudi Arabia
Keywords:Helicobacter pylori, urea breath test, serology, stool antigen test
AbstractHelicobacter pylori infection (H. Pylori) has a worldwide distribution, especially with gastric along with duodenal ulcers. It has been associated with various disorders such as anemia, coronary heart disease, and thyroid disease. There are limited local studies available evaluating the role and association of H. Pylori to various other diseases. Therefore, the current study aims to inspect comorbidities linked with H. Pylori infection in the Kingdom of Saudi Arabia. A prospective study was conducted by enrolling outpatients from Salman Bin Abdulaziz University Hospital and National Hospital in Riyadh. A total of 323 patients presenting with dyspeptic symptoms were recruited between 2012 and 2015. A questionnaire was utilized and distributed to study the possible dyspeptic symptoms among the participants. Initial evaluation included a liver function, complete blood count, lipid and thyroid profile test. H. Pylori diagnosis was founded on â€œurea breath testâ€, â€œH. Pylori stool ELISA testâ€, â€œserologyâ€, and â€œupper endoscopy with gastric biopsyâ€. Results were presented as P-values, mean +/- SD, and 95% confidence intervals using SPSS version 20. A total of 323 patients with â€œdyspepsiaâ€ or â€œsymptoms suggestive of gastritisâ€ were enrolled. Approximately, 166 (51.4%) patients were â€œPylori positiveâ€. The presence of positive H. Pylori was associated with frequent symptoms such as nausea, epigastric pain, vomiting, Dyspepsia, and bloating. Dyslipidemia, Anemia, diabetes, hypothyroidism, and hyperuricemia were more recurrent among the patients with H. Pylori infection. â€œMultivariate analysisâ€ demonstrated a relationship between Pylori infection and each of â€œbaseline cholesterol levelâ€, â€œdiabetesâ€, â€œhemoglobinâ€, and baseline â€œTSH levelsâ€. H. Pylori infection is considered to be common in Saudi Arabia. It is linked with dyslipidemia, diabetes, and hypothyroidism. In individuals with such disorders, H. Pylori management and testing are recommended. Prospective studies are needed in future to assess the benefit of eradication treatment as well as clinical implication of H. Pylori infection in the patients.
How to Cite
Al Dossari, K., Kamal, S., Al-Malki, A., & Al-Zahrani, J. (2016). Prevalence and Associated Factors of Pylori Infection in Symptomatic Patients Admitted to A Major Hospital in Saudi Arabia. Journal of Health Informatics in Developing Countries, 10(1). Retrieved from https://jhidc.org/index.php/jhidc/article/view/147
Authors retain copyright of the submission while granting the journal the right to publish it in the journal and in print.